About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

About PE-Fire 810
Along with APC/Fire 810™, PE/Fire™ 810 expands the range of spectral detection further than any of our previous fluorophores, emitting even beyond the range of PE/Cyanine7. Optimized for spectral unmixing cytometers, PE/Fire™ 810 is excited by the blue and yellow/green lasers and can utilized for nearly any antigen since it has little spectral overlap with other fluorophores. While we have released several PE tandem options, our data below shows PE/Fire™ 810 can be unmixed from them in a multicolor panel.