KLRG1 / APC-Fire 810 / SA231A2
Product Details
Description | APC/Fire 810 anti-human KLRG1 (MAFA) | |
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Conjugate | APC-Fire 810 | |
Clone | SA231A2 | |
Target Species | Human | |
Applications | FC | |
Supplier | BioLegend | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About KLRG1
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [provided by RefSeq, Jun 2016]
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [provided by RefSeq, Jun 2016]
About APC-Fire 810
APC-Fire™ 810 from BioLegend has an excitation peak at 650nm and an emission peak at 807 nm and is spectrally similar to APC-CF®790. APC-Fire™ 810 is most commonly used in flow cytometry. On a 5-laser Cytek® Aurora, it has very limited spectral spillover into any other channel, so it can be assigned to any antigen with moderate to abundant expression and used in combination with any other fluorophore. This dye is very useful for detecting variably expressed markers, like markers of activation, since it emits so far outside of the autofluorescence range.
APC-Fire™ 810 from BioLegend has an excitation peak at 650nm and an emission peak at 807 nm and is spectrally similar to APC-CF®790. APC-Fire™ 810 is most commonly used in flow cytometry. On a 5-laser Cytek® Aurora, it has very limited spectral spillover into any other channel, so it can be assigned to any antigen with moderate to abundant expression and used in combination with any other fluorophore. This dye is very useful for detecting variably expressed markers, like markers of activation, since it emits so far outside of the autofluorescence range.
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