CD8a / StarBright Violet 570 / KT15

Product Details
Description RAT ANTI MOUSE CD8 ALPHA:StarBright Violet 570
Conjugate StarBright Violet 570
Clone KT15
Target Species Mouse
Applications FC
Supplier Bio-Rad
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About CD8a
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
About StarBright Violet 570
StarBright Violet 570 (SBV570) is a fluorescent polymer nanoparticle that has an excitation peak at 404 nm and an emission peak at 571 nm, spectrally comparable to BV570. The StarBright family fluorophores from Bio-Rad offers an alternative to the Horizon Brilliantâ„¢ polymer series from BD Biosciences including Brilliantâ„¢ UV and Brilliantâ„¢ Violet.
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