CD4 / StarBright Violet 710 / RM4-5

Product Details
Description RAT ANTI MOUSE CD4:StarBright Violet 710
Conjugate StarBright Violet 710
Clone RM4-5
Target Species Mouse
Applications FC
Supplier Bio-Rad
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About CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
About StarBright Violet 710
StarBright Violet 710 (SBV710) is a fluorescent polymer nanoparticle that has an excitation peak at 402 nm and an emission peak at 713 nm, spectrally comparable to SuperBright 702 and BV711. The StarBright family fluorophores from Bio-Rad offers an alternative to the Horizon Brilliantâ„¢ polymer series from BD Biosciences including Brilliantâ„¢ UV and Brilliantâ„¢ Violet.
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