Ku70 / Biotin /
Product Details
| Description | XRCC6 (X-ray Repair Cross-complementing Protein 6, 5'-deoxyribose-5-phosphate Lyase Ku70, 5'-dRP Lyase Ku70, 70kD Subunit of Ku Antigen, ATP-dependent DNA Helicase 2 Subunit 1, ATP-dependent DNA Helicase II 70kD Subunit, CTC box-binding Factor 75kD Subunit, CTC75, CTCBF, DNA Repair Protein XRCC6, Lupus Ku Autoantigen Protein p70, Ku70, Thyroid-lupus Autoantigen, TLAA, X-ray Repair Complementing Defective Repair in Chinese Hamster Cells 6, G22P1) (Biotin) Pab | |
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| Conjugate | Biotin | |
| Clone | ||
| Target Species | Human | |
| Applications | WB | |
| Supplier | US Biological | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About Ku70
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
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