TRADD / Biotin / 3G1
Product Details
| Description | TRADD (Tumor Necrosis Factor Receptor Type 1-associated DEATH Domain Protein, TNFR1-associated DEATH Domain Protein, TNFRSF1A-associated Via Death Domain) (Biotin) Mab 3G1 | |
|---|---|---|
| Conjugate | Biotin | |
| Clone | 3G1 | |
| Target Species | Human | |
| Applications | ELISA, WB | |
| Supplier | US Biological | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About TRADD
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
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