CD263 / MaxLight 550 /

Product Details
Description TNFRSF10C (Tumor Necrosis Factor Receptor Superfamily Member 10C, LIT, DCR1, TRID, CD263, TRAILR3, TRAIL-R3, DCR1-TNFR) (MaxLight 550) Pab
Conjugate MaxLight 550
Clone
Target Species Human
Applications WB, IHC
Supplier US Biological
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About CD263
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]
About MaxLight 550
MaxLight 550 is excited by the 561 laser and emission captured by the 585/42 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy.
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