HNF-1 / HRP / 4i63, 7H3

Product Details
Description TCF 1 (T-cell Factor 1) (HRP) Mab 4i63, 7H3
Conjugate HRP
Clone 4i63, 7H3
Target Species Human
Applications ELISA, WB, IHC
Supplier US Biological
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About HNF-1
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
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