CD137 Monoclonal / Biotin / 17B5-1H1
Product Details
| Description | Clone 17B5-1H1 reacts with mouse CD137, also known as 4-1BB or TNFRSF9, a member of the TNFR superfamily. It is expressed on the cell surface of T cells upon activation. The interaction of CD137 with its ligand, 4-1BBL, on antigen presenting cells (APCs) delivers a bidirectional costimulatory signal. CD137 engagement is shown to be required for CD8+ T cell survival and memory formation. The monoclonal antibody 17B5 is reported to have strong antagonistic effect in in vitro functional assays. | |
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| Conjugate | Biotin | |
| Clone | 17B5-1H1 | |
| Target Species | Mouse | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
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