FPR1 Monoclonal / APC / REA169

Product Details
Description Clone REA169 recognizes N-formyl-L-methionyl-L-leucyl-phenylalanine receptor (fMLP receptor), which is a seven transmembrane G-protein coupled receptor. fMLP receptor binds formylated peptides such as fMLP, which originate from degraded bacterial or mitochondrial proteins and mediate inflammatory reactions, activation of neutrophils and trafficking of leukocytes to the site of inflammation. Expression of fMLP receptor is mainly found on leukocytes, neutrophils and monocytes. | Additional Information: Clone REA169 displays negligible binding to Fc receptors. |
Conjugate APC
Clone REA169
Target Species Human
Applications FC
Supplier Miltenyi Biotec
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About FPR1
This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010]
About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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Validation References
PMID 14556648
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