STAT6 / HRP / 4G7

Product Details
Description STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced, D12S1644, IL-4-STAT, STAT6B, STAT6C) (HRP) Mab 4G7
Conjugate HRP
Clone 4G7
Target Species Human
Applications ELISA, IF, WB
Supplier US Biological
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About STAT6
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
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574 STAT6 antibodies from over 31 suppliers available with over 55 conjugates.

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