CD45RB Monoclonal / PE-Vio770 / REA119
Product Details
| Description | Clone REA119 recognizes CD45RB, which is a splice variant isoform of CD45, the leukocyte common antigen (LCA). CD45 is a haemopoietic cell specific protein tyrosine phosphatase, and regulates various signaling events through cytokine receptors and in response to cellular adhesion. Expression of CD45RB is found on T cell subset, B cells, monocytes/macrophages, granulocytes, and dendritic cells. | Additional information: Clone REA119 displays negligible binding to Fc receptors. | | |
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| Conjugate | PE-Vio770 | |
| Clone | REA119 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
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About PE-Vio770
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.
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Validation References
| PMID 1531636 | |
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| PMID 18840711 | |
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