Ly-6B.2 Monoclonal / APC-Vio770 / REA115

Product Details

Description	Clone REA115 recognizes Ly-6B.2, a member of the lymphocyte antigen 6 (Ly-6) superfamily and is located on chromosome 15 as the other members of the murine Ly-6 family. The Ly-6 family members are normally GPI-anchored, cysteine-rich cell surface molecules. Expression of Ly-6B.2 antigen has been reported on neutrophils, bone marrow restricted progenitors, monocytes, and is lost during the differentiation of monoytes into tissue resident macrophages or dendritic cell phenotype. High expression of Ly-6B.2 is also associated with inflammatory cell repertoire including monocytes and certain populations of activated macrophages present during infections. \| Additional information: Clone REA115 displays negligible binding to Fc receptors.
Conjugate	APC-Vio770
Clone	REA115
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
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About APC-Vio770
APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.

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