CD200 R3 Monoclonal / APC-Vio770 / REA128
Product Details
Description | Clone REA128 recognizes the human CD200R3 antigen. CD200R is an approximately 33 kDa single-pass type I membrane-protein which is a disulfide-linked dimer on the cell surface. It is reported, that the four different isoforms of CD200R (CD200R1, CD200R2, CD200R3, CD200R4) bind to CD200 (OX-2) as ligand. CD200 is primarily expressed on myeloid cells but also expressed on T and B lymphocytes. The combination of CD200R and CD200 inhibits mast cell degranulation, promotes macrophage activation, and decreases the activation of lymphocytes. | Additional information: Clone REA128 displays negligible binding to Fc receptors. | | |
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Conjugate | APC-Vio770 | |
Clone | REA128 | |
Target Species | Mouse | |
Applications | FC | |
Supplier | Miltenyi Biotec | |
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About APC-Vio770
APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.
APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.
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Validation References
PMID 12960329 | |
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PMID 15187158 | |
PMID 17714785 | |
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