CD131 Monoclonal / APC / REA193

Product Details
Description Clone REA193 recognizes CD131, the IL-3 receptor beta subunit. CD131 is a single-pass type I transmembrane protein, belongs to the cytokine receptor superfamily, and is shared by IL-3, IL-5, and GM-CSF receptors. The receptor-specific alpha subunits is mainly involved in ligand binding and the common beta subunit, CD131, is important for transducing the signal initiated by binding of the ligands to respective receptors. | Additional information: Clone REA193 displays negligible binding to Fc receptors. |
Conjugate APC
Clone REA193
Target Species Mouse
Applications FC
Supplier Miltenyi Biotec
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About CD131
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008]
About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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Validation References
PMID 8466757
PMID 9766809
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336 CD131 antibodies from over 25 suppliers available with over 57 conjugates.

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