CD172a / Biotin / 10B870, 15-414
Product Details
| Description | SIRP alpha (Signal Regulatory Protein alpha, SIRPalpha, SIRPA, Signal Regulatory Protein alpha Type 1, Signal Regulatory Protein alpha 1, SIRP alpha 1, SIRPalpha1, Signal Regulatory Protein alpha Type 2, SIRP alpha 2, SIRPalpha2, SIRP alpha 3, Brain Immunoglobulin-like Molecule with Tyrosine-based Activation Motifs, Brain Ig-like Molecule with Tyrosine-based Activation Motifs, BIT, CD172a, CD172a Antigen, Inhibitory Receptor SHPS-1, Inhibitory Receptor SHPS1, Macrophage Fusion Receptor, MFR, MYD-1, Myd-1 Antigen, MYD1, Myd1 Antigen, p84, Protein Tyrosine Phosphatase Non-receptor Type Substrate 1, PTPNS1, SHP Substrate 1, SHPS1, SHPS-1, Tyrosine Phosphatase SHP Substrate 1, Tyrosine Protein Phosphatase Non-receptor Type Substrate 1, Tyrosine Protein Phosphatase Non-receptor Type Substrate) (Biotin) Mab 10B870, 15-414 | |
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| Conjugate | Biotin | |
| Clone | 10B870, 15-414 | |
| Target Species | Human | |
| Applications | IHC | |
| Supplier | US Biological | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD172a
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 2008]
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