SIAH1 / PE / 2C5

Product Details
Description SIAH1 (Seven in Absentia Homolog 1 (Drosophila), FLJ08065, HUMSIAH, Siah-1, Siah-1a, hSIAH1) (PE) Mab 2C5
Conjugate PE
Clone 2C5
Target Species Human
Applications ELISA, WB
Supplier US Biological
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About SIAH1
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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178 SIAH1 antibodies from over 15 suppliers available with over 23 conjugates.

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