CD24 Monoclonal / APC / REA405

Product Details
Description Clone REA405 recognizes the rat CD24 antigen which is expressed on the surface of cells committed to the B lineage but not on cells of other hematopoietic lineages. CD24 is a glycosyl phosphatidylinositol-anchored cell adhesion molecule which is also known as Heat-stable antigen (HSA) or Nectadrin. It exists in multiple glycoforms and plays an important role in hematopoietic and neural cell development. | Additional information: Clone REA405 displays negligible binding to Fc receptors.
Conjugate APC
Clone REA405
Target Species Rat
Applications FC
Supplier Miltenyi Biotec
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About CD24
This gene encodes a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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Validation References
PMID 8292828
PMID 9004038
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