Semaphorin 6D / Biotin /

Product Details
Description SEMA6D, NT (SEMA6D, KIAA1479, Semaphorin-6D) (Biotin) Pab
Conjugate Biotin
Clone
Target Species Human
Applications ELISA, WB
Supplier US Biological
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About Semaphorin 6D
Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010]
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134 Semaphorin 6D antibodies from over 14 suppliers available with over 27 conjugates.

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