CD158e/k Monoclonal / PE / 5.133

Product Details
Description Clone 5.133 reacts with CD158e (KIR3DL1) and CD158k (KIR3DL2), members of the killer immunoglobulin-like receptor (KIR) family which recognizes subsets of HLA alleles. The family of killer immunoglobulin-like receptors (KIR) contributes to the regulation of NK cell-mediated cytotoxicity. Expression is found mainly on CD56dimCD16+ natural killer (NK) cells but also on a subset of CD8+ T cells. They are monomeric receptors possessing high allelic polymorphism with either 2 or 3 Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be subdivided in inhibitory KIRs and activating KIRs.
Conjugate PE
Clone 5.133
Target Species Human
Applications FC
Supplier Miltenyi Biotec
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About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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20 CD158e/k antibodies available with over 8 conjugates.

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