RUNX3 / PE /
Product Details
| Description | RUNX3 (Acute Myeloid Leukemia 2 Protein, Acute Myeloid Leukemia Gene 2, AML 2, AML2, CBF alpha 3, CBF-alpha-3, CBFA 3, CBFA3, Core Binding Factor alpha 3 Subunit, Core Binding Factor, Core Binding Factor Runt Domain alpha Subunit 3, Core Binding Factor Subunit alpha 3, Core-binding Factor, Core-binding Factor Subunit alpha-3, Oncogene AML 2, Oncogene AML-2, PEA2 alpha C, PEA2-alpha C, PEBP2 alpha C, PEBP2-alpha C, Pebp2a3, PEBP2aC, Polyomavirus Enhancer Binding Protein 2 alpha C Subunit, Polyomavirus Enhancer-binding Protein 2 alpha C Subunit, Runt Domain alpha Subunit 3, Runt Related Transcription Factor 3, Runt-related Transcription Factor 3, RUNX 3, Runx3, SL3 3 Enhancer Factor 1 alpha C Subunit, SL3-3 Enhancer Factor 1 alpha C Subunit, SL3/AKV Core Binding Factor alpha C Subunit, SL3/AKV Core-binding Factor alpha C Subunit, Transcription Factor AML2) Pab | | | |
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| Conjugate | PE | |
| Clone | ||
| Target Species | Human | |
| Applications | ELISA, WB | |
| Supplier | US Biological | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About RUNX3
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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