RUNX3 / PE /

Product Details
Description RUNX3 (Runt-Related Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, Core-Binding Factor Subunit alpha-3, CBF-alpha-3, Oncogene AML-2, Polyomavirus Enhancer-Binding Protein 2 alpha C Subunit, PEA2-alpha C, PEBP2-alpha C, SL3-3 Enhancer Factor 1 alpha C Subunit, SL3/AKV Core-Binding Factor alpha C Subunit, RUNX3, AML2, CBFA3, PEBP2A3) Pab | |
Conjugate PE
Clone
Target Species Human
Applications WB
Supplier US Biological
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About RUNX3
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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352 RUNX3 antibodies from over 24 suppliers available with over 43 conjugates.

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