CD231 Monoclonal / Biotin / SN1a
Product Details
Description | The monoclonal antibody SN1a reacts with the 150 kDa glycoprotein CD231 also known as T cell–acute lymphoblastic leukemia specific antigen (TALLA), which is a member of the tetraspanin family. CD231 is expressed on T cell–type acute lymphoblastic leukemia (T-ALL) cells, skeletal muscle cells, brain, and spleen. It is reported that TALLA plays a role in integrin-mediated migration and can associate with phosphoinositide 4-kinase. | |
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Conjugate | Biotin | |
Clone | SN1a | |
Target Species | Human | |
Applications | FC | |
Supplier | Miltenyi Biotec | |
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About CD231
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked cognitive disability and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked cognitive disability and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy. [provided by RefSeq, Jul 2008]
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Validation References
PMID 2440562 | |
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PMID 3494997 | |
PMID 6600841 | |
PMID 7768645 | |
PMID 11042117 | |
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