CD205 Monoclonal / Biotin / HD30
Product Details
| Description | Clone HD30 detects the CD205 glycoprotein. CD205, also known as DEC205 or Ly-75, is a 210 kDa C-type lectin single-pass membrane protein (type I), which is highly expressed on thymic epithelial cells and dendritic cells. Unlike murine CD205, human CD205 is also found at low levels on other peripheral blood lymphocytes, e.g., monocytes, T cells, B cells, and NK cells. CD205 belongs to the macrophage mannose receptor family and acts as an endocytic receptor to uptake antigens, direct the captured antigens from the extracellular space to the antigen-processing compartment for antigen presentation on MHC class II and cross-presentation on MHC class I molecules. Another function of CD205 is the clearance of apoptotic cells, potentially an important pathway for the uptake of self-antigen in intrathymic and peripheral tolerance. | |
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| Conjugate | Biotin | |
| Clone | HD30 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD205
Predicted to enable signaling receptor activity. Predicted to be involved in immune response and inflammatory response. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Predicted to enable signaling receptor activity. Predicted to be involved in immune response and inflammatory response. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
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Validation References
| PMID 10980384 | |
|---|---|
| PMID 15024047 | |
| PMID 15233723 | |
| PMID 19135256 | |
| Additional Sources |
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Reviews & Ratings
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