CD32 Monoclonal / Biotin / 2E1
Product Details
Description | CD32, also known as FcgammaRII, is a 40 kDa low affinity receptor for the Fc fragment of aggregated IgG. Due to alternative splicing three different isoforms of CD32 are expressed on hematopoietic cells: FcRIIA, FcRIIB, and FcRIIC. The cytoplasmic domains of FcRIIA and FcRIIC contain an activatory ITAM motif whereas FcRIIB is an inhibitory receptor containing an ITIM motif. Different isoforms of CD32 are expressed on B cells, monocytes, dendritic cells, granulocytes, and platelets. The monoclonal antibody 2E1 recognizes all isoforms of CD32 without blocking the binding of immune complexes. | |
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Conjugate | Biotin | |
Clone | 2E1 | |
Target Species | Human | |
Applications | FC | |
Supplier | Miltenyi Biotec | |
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Validation References
PMID 8283039 | |
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PMID 12960360 | |
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