CD51/CD61 Monoclonal / PE / 23C6

Product Details
Description The monoclonal antibody 23C6 recognizes the human heterodimeric complex CD51/CD61, also known as integrin alphav/beta3. The dimers are expressed on melanoma cells, endothelial cells, on osteoclasts, and in a very low density on platelets. The CD51/CD61 complex mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, osteopontin, and collagen.
Conjugate PE
Clone 23C6
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Supplier Miltenyi Biotec
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About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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Validation References
PMID 1689599
PMID 7683273
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91 CD51/CD61 antibodies from over 12 suppliers available with over 32 conjugates.

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