CD310 Monoclonal / APC / AFL4

Product Details
Description The AFL4 monoclonal antibody reacts with mouse VEGFR-3, a member of the receptor tyrosine kinase family. This 195 kDa molecule is also known as Flt-4. During early embryogenesis all endothelial cells express VEGFR-3, while in the adult tissues, VEGFR-3 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. VEGFR-3 expression is also induced upon tumor angiogenesis. VEGF-C and VEGF-D are ligands for VEGFR-3.
Conjugate APC
Clone AFL4
Target Species Mouse
Applications FC
Supplier Miltenyi Biotec
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About CD310
This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008]
About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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Validation References
PMID 10887117
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