CD23 Monoclonal / PE / B3B4

Product Details
Description The monoclonal antibody B3B4 recognizes CD23, also known as low affinity IgE Fc receptor (FcepsilonRII), a type II integral membrane glycoprotein. CD23 is expressed on mature B cells, but not on CD5+ B-1 cells, activated B cells, follicular dendritic cells of immunized mice and on a subset of splenic dendritic cells. Clone B3B4 is reported to block IgE binding to FcepsilonRII.
Conjugate PE
Clone B3B4
Target Species Mouse
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC
Supplier Miltenyi Biotec
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About CD23
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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1135 CD23 antibodies from over 45 suppliers available with over 94 conjugates.

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