PSMD11 / HRP /

Product Details
Description PSMD11, CT (26S Proteasome Non-ATPase Regulatory Subunit 11, 26S Proteasome Regulatory Subunit S9, 26S Proteasome Regulatory Subunit RPN6, 26S Proteasome Regulatory Subunit p44.5) (HRP) Pab
Conjugate HRP
Clone
Target Species Human
Applications ELISA, WB, IHC
Supplier US Biological
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About PSMD11
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
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