PSMC6 / Biotin /

Product Details
Description PSMC6 (Proteasome 26S Subunit ATPase 6, 26S Protease Regulatory Subunit 10B, P44, p42, SUG2, CADP44) (Biotin) Pab
Conjugate Biotin
Clone
Target Species Human
Applications WB, IHC
Supplier US Biological
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About PSMC6
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12. [provided by RefSeq, Jul 2008]
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205 PSMC6 antibodies from over 17 suppliers available with over 35 conjugates.

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