CD158e Monoclonal / Unconjugated / DX9
Product Details
| Description | Clone DX9 recognizes CD158e (KIR3DL1), a member of the killer immunoglobulin-like receptor (KIR) family expressed on CD56dimCD16+ natural killer (NK) cells and CD8+ T cells. KIRs contribute to the regulation of NK cell-mediated cytotoxicity. They are monomeric receptors possessing high allelic polymorphism with either 2 or 3 Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be further subdivided into inhibitory KIRs and activating KIRs (KIR2DS or KIR3DS). KIR3DL1 provides an inhibitory signal of NK cell lytic activity upon interaction with its specific ligand, HLA-Bw4. | |
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| Conjugate | Unconjugated | |
| Clone | DX9 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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Validation References
| PMID 9059894 | |
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| PMID 11895890 | |
| PMID 12200350 | |
| PMID 12493005 | |
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85 CD158e antibodies from over 8 suppliers available with over 20 conjugates.
