CD30 Monoclonal / VioBlue / Ki-2

Product Details
Description The CD30 antibody recognizes the human CD30 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily also known as the Ki-1, which is found on Hodgkin/Reed-Sternberg (H/RS) cells as well as on activated T and B lymphocytes.
Conjugate VioBlue
Clone Ki-2
Target Species Human
Applications FC
Supplier Miltenyi Biotec
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About CD30
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
About VioBlue
Vio®Blue® has an excitation peak at 400 nm and an emission peak at 455 nm, and is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), V450 (BD Biosciences), Alexa Fluor™ 405 (ThermoFisher), Pacific Blue (ThermoFisher Scientific) and ATTO 425 (AttoTec).
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Validation References
PMID 11901204
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1343 CD30 antibodies from over 38 suppliers available with over 69 conjugates.

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