CD169 Monoclonal / PE-Vio770 / 7-239

Product Details
Description The monoclonal antibody 7-239 reacts with CD169, also known as siglec-1 or sialoadhesin, which is a type I transmembrane glycoprotein. It is the largest member of the siglec family, which are cell surface lectins that are able to bind to sialic acids and mediate interactions between proteins and carbohydrates. Siglec-1 is mainly expressed on tissue macrophages and dendritic cells and interacts with its counterreceptor on T cells, which has been identified as CD43.
Conjugate PE-Vio770
Clone 7-239
Target Species Human
Applications FC
Supplier Miltenyi Biotec
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About CD169
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]
About PE-Vio770
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.
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674 CD169 antibodies from over 29 suppliers available with over 79 conjugates.

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