IL-18 R alpha Monoclonal / Biotin / H44
Product Details
| Description | Clone H44 recognizes the CD218 antigen, which is also known as interleukin-18 receptor alpha chain (IL-18Ralpha) receptor, is an heterodimeric receptor complex and composed of the IL-18Ralpha chain and the IL-1 receptor accessory protein-like (IL-1RacPL) or IL-18Rbeta chain. CD218 represents the ligand-binding chain, whereas IL-18Rbeta is suggested to assist in the formation of a high affinity complex and mediates intracellular signals. IL-18R is expressed on a variety of cells including macrophages, neutrophils, natural killer (NK) cells, endothelial, and smooth muscle cells and an upregulated expression is observed on naive T cells, T helper cell type 1 (TĘś1) cells, and B cells, in the presence of IL-12. | |
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| Conjugate | Biotin | |
| Clone | H44 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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Validation References
| PMID 10865972 | |
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| PMID 11123287 | |
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