IL-9 Monoclonal / APC / MH9D1

Product Details
Description Interleukin 9 (IL-9) is secreted by mast cells and T helper (Tʜ) cells. First, IL-9 production was associated to Tʜ2 cells, but it was also found in other Tʜ subsets. Recently, evidence for the existence of a specialized lineage of Tʜ cells producing IL-9, named Tʜ9, came up. IL-9 has pleiotropic effects, e.g., it promotes mast cell growth and function, is involved in CD4+ T cell subset differentiation and growth, enhances IgE production, supports hematopoiesis, and acts on airway and gut epithelial cells.
Conjugate APC
Clone MH9D1
Target Species Human
Applications FC
Supplier Miltenyi Biotec
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About IL-9
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq, Jul 2008]
About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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621 IL-9 antibodies from over 27 suppliers available with over 51 conjugates.

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