CD93 Monoclonal / Biotin / VIMD2

Product Details

Description	The monoclonal antibody VIMD2 reacts with human CD93, also known as C1qRp, which is a 120 kDa heavily O-glycosylated protein. It is expressed on myeloid cells, platelets, endothelial cells, and immature dendritic cells whereas mature dendritic cells show weak to negative CD93 expression. C1qRp is involved in regulation of phagocytic activity, macrophage activation, and cell-cell adhesion.
Conjugate	Biotin
Clone	VIMD2
Target Species	Human
Applications	FC
Supplier	Miltenyi Biotec
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About CD93
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq, Jul 2008]

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