CD83 Monoclonal / Biotin / HB15
Product Details
| Description | The CD83 antibody reacts with a 45 kDa glycoprotein member of the immunoglobulin superfamily of receptors, also known as HB15. In humans, CD83 is expressed on the surface of activated dendritic cells (DCs) and can therefore be used as a marker for the phenotypical characterization of DC maturation. CD83 plays a role in antigen presentation and lymphocyte activation. | |
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| Conjugate | Biotin | |
| Clone | HB15 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | Miltenyi Biotec | |
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About CD83
The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
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Validation References
| PMID 1378080 | |
|---|---|
| PMID 7706722 | |
| PMID 8145033 | |
| PMID 12072358 | |
| PMID 15320871 | |
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