CLEC9A Monoclonal / Biotin / 7H11
Product Details
Description | Clone 7H11 recognizes CD370 C-type lectin 9A (CLEC9A), also known as DC NK lectin group receptor-1 (DNGR-1). It is a protein of 264 amino acids expressed at high level on CD8a+ dendritic cells and at lower level on mPDCA-1+ plasmacytoid dendritic cells. CD370 (CLEC9A) recognizes necrotic cell associated epitopes and plays an important role in crosspresentation of dead cell derived antigens. | |
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Conjugate | Biotin | |
Clone | 7H11 | |
Target Species | Mouse | |
Applications | FC | |
Supplier | Miltenyi Biotec | |
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About CLEC9A
CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008]
CLEC9A is a group V C-type lectin-like receptor (CTLR) that functions as an activation receptor and is expressed on myeloid lineage cells (Huysamen et al., 2008 [PubMed 18408006]).[supplied by OMIM, Aug 2008]
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Validation References
PMID 18497879 | |
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PMID 19219027 | |
PMID 20333625 | |
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