PDZK1 / APC /

Product Details
Description PDZK1 (PDZ Domain-containing Protein 1, CFTR-associated Protein of 70kD, CAP70, CLAMP, PDZD1, NHERF3, NHERF-3) (APC) Pab
Conjugate APC
Clone
Target Species Human
Applications WB, IHC
Supplier US Biological
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About PDZK1
This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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200 PDZK1 antibodies from over 15 suppliers available with over 40 conjugates.

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