PCNA / Biotin / 2Q2Q19799, PC10
Product Details
| Description | PCNA (Proliferating Cell Nuclear Antigen) (Biotin) Mab 2Q2Q19799, PC10 | |
|---|---|---|
| Conjugate | Biotin | |
| Clone | 2Q2Q19799, PC10 | |
| Target Species | Rat | |
| Applications | WB, IHC | |
| Supplier | US Biological | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About PCNA
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
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