NQO1 / APC / A180

Product Details
Description NQO1 (NAD(P)H Dehydrogenase Quinone 1, Azoreductase, Cytochrome b-5 Reductase, DHQU, Diaphorase (NADH/NADPH) (Cytochrome b-5 Reductase), Diaphorase 4, DIA4, Dioxin Inducible 1, DT Diaphorase, DTD, Menadione Reductase, NAD(P)H Menadione Oxidoreductase 1 Dioxin Inducible, NAD(P)H: Menadione Oxidoreductase 1 Dioxin Inducible 1, NMOR1, NMORI, NAD(P)H: Quinone Acceptor Oxidoreductase Type 1, NAD(P)H: Quinone Oxidoreductase 1, Phylloquinone Reductase, Quinone Reductase 1, QR1) (APC) Mab A180
Conjugate APC
Clone A180
Target Species Human
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Supplier US Biological
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About NQO1
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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