NDE1 / PE / 2G11-1C11

Product Details
Description NDE1 (Nuclear Distribution Protein nudE Homolog 1, NudE, NUDE, FLJ20101, HOM-TES-87) (PE) Mab 2G11-1C11
Conjugate PE
Clone 2G11-1C11
Target Species Human
Applications ELISA, IF, WB
Supplier US Biological
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About NDE1
This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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126 NDE1 antibodies from over 16 suppliers available with over 12 conjugates.

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