MAP4K4 / Biotin /

Product Details
Description MAP4K4 (Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, HGK, NIK, MEKKK4, FLH21957, MAP4K4, FLJ10410, FLJ20373, FLJ90111, KIAA0687) (Biotin) Pab
Conjugate Biotin
Clone
Target Species Human
Applications WB
Supplier US Biological
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About MAP4K4
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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175 MAP4K4 antibodies from over 16 suppliers available with over 12 conjugates.

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