CD11b / APC-Alexa 750 / Bear1
Product Details
| Description | CD11b Human (Bear1); IOTest ; APC-Alexa Fluor* 750 ; 0.5 mL ; Liquid ; ASR | |
|---|---|---|
| Conjugate | APC-Alexa 750 | |
| Clone | Bear1 | |
| Target Species | Human | |
| Applications | ||
| Supplier | Beckman Coulter | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
About APC-Alexa 750
APC-Alexa 750 from Thermo Fisher Scientific has an excitation peak at 651 nm and an emission peak at 775 nm and is most commonly used in flow cytometry.
APC-Alexa 750 from Thermo Fisher Scientific has an excitation peak at 651 nm and an emission peak at 775 nm and is most commonly used in flow cytometry.
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