IL-12 R beta 1 / HRP /

Product Details
Description IL12RB1 (Interleukin 12 Receptor beta 1, CD212, IMD30, IL12RB, IL-12R-BETA1, Interleukin-12 Receptor Subunit beta-1) (HRP). Pab
Conjugate HRP
Clone
Target Species Human
Applications WB, IHC
Supplier US Biological
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About IL-12 R beta 1
The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
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324 IL-12 R beta 1 antibodies from over 19 suppliers available with over 54 conjugates.

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