CD221 / Biotin /

Product Details
Description IGF1R, NT (K66) (IGF1R, Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, CD221, Insulin-like growth factor 1 receptor alpha chain, Insulin-like growth factor 1 receptor beta chain) (Biotin) Pab
Conjugate Biotin
Clone
Target Species Human
Applications ELISA, IF, WB, IHC
Supplier US Biological
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About CD221
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
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923 CD221 antibodies from over 28 suppliers available with over 48 conjugates.

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