HNF-1 beta / PE /

Product Details
Description TCF2 (Hepatocyte Nuclear Factor 1-beta, HNF-1-beta, HNF-1B, Homeoprotein LFB3, Transcription Factor 2, TCF-2, Variant Hepatic Nuclear Factor 1, vHNF1, HNF1B) (PE) Pab
Conjugate PE
Clone
Target Species Human
Applications WB
Supplier US Biological
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About HNF-1 beta
This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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185 HNF-1 beta antibodies from over 15 suppliers available with over 18 conjugates.

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