FBLN5 / MaxLight 750 /

Product Details
Description Fibulin-5 (FIBL-5, Developmental Arteries and Neural Crest EGF-like Protein, Dance, Urine p50 Protein, UP50, FBLN5, DANCE, UNQ184/PRO210) (MaxLight 750) Pab
Conjugate MaxLight 750
Clone
Target Species Human
Applications WB
Supplier US Biological
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About FBLN5
The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008]
About MaxLight 750
MaxLight 750 is excited by the laser and emission captured by the 780/60 filter. It can be used with the following analysis platforms: Labeling, Flow Cytometry, Fluorescence Microscopy, Fluorescence Microscopy.
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