CD11b / Brilliant Blue 515 / ICRF44

Product Details
Description BB515 Mouse Anti-Human CD11b
Conjugate Brilliant Blue 515
Clone ICRF44
Target Species Cynomolgus, Human, Rhesus
Applications FC
Supplier BD Biosciences
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About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
About Brilliant Blue 515
Horizon Brilliantâ„¢ Blue 515 (BB515), exclusive to BD Biosciences, is a brighter alternative to FITC and Alexa Fluorâ„¢ 488 in flow cytometry. It has an excitation peak at 590 nm and an emission peak at 515 nm.
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