CD11b / APC-R700 / M1/70
Product Details
Description | APC-R700 Rat Anti-CD11b | |
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Conjugate | APC-R700 | |
Clone | M1/70 | |
Target Species | Human, Mouse | |
Applications | FC | |
Supplier | BD Biosciences | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
About APC-R700
APC-R700 from BD Biosciences has an excitation peak at 651 nm and an emission peak at 705 nm. It's useful in flow cytometry and is spectrally similar to APC-Cy5.5, APC-Alexa 700, APC-Alexa 680 and Seta-APC-705.
APC-R700 from BD Biosciences has an excitation peak at 651 nm and an emission peak at 705 nm. It's useful in flow cytometry and is spectrally similar to APC-Cy5.5, APC-Alexa 700, APC-Alexa 680 and Seta-APC-705.
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